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Comparing the efficacy and neuroinflammatory potential of three anti-abeta antibodies

Immunotherapy is a promising strategy for the treatment of Alzheimer’s disease (AD). Antibodies directed against Amyloid Beta (Aβ) are able to successfully clear plaques and reverse cognitive deficits in mouse models. Excitement towards this approach has been tempered by high profile failures in the...

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Detalles Bibliográficos
Autores principales: Fuller, James P., Stavenhagen, Jeffrey B., Christensen, Søren, Kartberg, Fredrik, Glennie, Martin J., Teeling, Jessica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612324/
https://www.ncbi.nlm.nih.gov/pubmed/26433971
http://dx.doi.org/10.1007/s00401-015-1484-2