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Is CMV a target in pediatric glioblastoma? Expression of CMV proteins, pp65 and IE1-72 and CMV nucleic acids in a cohort of pediatric glioblastoma patients

While the 5-year overall survival is better in pediatric than in adult patients diagnosed with glioblastoma (GBM), outcomes in children remain very poor. Understanding the mechanisms of tumorigenesis and tumor propagation can identify therapeutic targets to improve these outcomes. Human cytomegalovi...

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Detalles Bibliográficos
Autores principales: Wakefield, Amanda, Pignata, Antonella, Ghazi, Alexia, Ashoori, Aidin, Hegde, Meenakshi, Landi, Daniel, Gray, Tara, Scheurer, Michael E., Chintagumpala, Murali, Adesina, Adekunle, Gottschalk, Stephen, Hicks, John, Powell, Suzanne Z., Ahmed, Nabil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612329/
https://www.ncbi.nlm.nih.gov/pubmed/26341370
http://dx.doi.org/10.1007/s11060-015-1905-z