Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies

Pathological tau aggregation leads to filamentous tau inclusions and characterizes neurodegenerative tauopathies such as Alzheimer’s disease and frontotemporal dementia and parkinsonism linked to chromosome 17. Tau aggregation coincides with clinical symptoms and is thought to mediate neurodegenerat...

Descripción completa

Detalles Bibliográficos
Autores principales: Wagner, Jens, Krauss, Sybille, Shi, Song, Ryazanov, Sergey, Steffen, Julia, Miklitz, Carolin, Leonov, Andrei, Kleinknecht, Alexander, Göricke, Bettina, Weishaupt, Jochen H., Weckbecker, Daniel, Reiner, Anne M., Zinth, Wolfgang, Levin, Johannes, Ehninger, Dan, Remy, Stefan, Kretzschmar, Hans A., Griesinger, Christian, Giese, Armin, Fuhrmann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612332/
https://www.ncbi.nlm.nih.gov/pubmed/26439832
http://dx.doi.org/10.1007/s00401-015-1483-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612332/
https://www.ncbi.nlm.nih.gov/pubmed/26439832
http://dx.doi.org/10.1007/s00401-015-1483-3

Ejemplares similares