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Genome-wide mapping reveals single-origin chromosome replication in Leishmania, a eukaryotic microbe

BACKGROUND: DNA replication initiates on defined genome sites, termed origins. Origin usage appears to follow common rules in the eukaryotic organisms examined to date: all chromosomes are replicated from multiple origins, which display variations in firing efficiency and are selected from a larger...

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Detalles Bibliográficos
Autores principales: Marques, Catarina A., Dickens, Nicholas J., Paape, Daniel, Campbell, Samantha J., McCulloch, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612428/
https://www.ncbi.nlm.nih.gov/pubmed/26481451
http://dx.doi.org/10.1186/s13059-015-0788-9