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PRP4K is a HER2-regulated modifier of taxane sensitivity

The taxanes are used alone or in combination with anthracyclines or platinum drugs to treat breast and ovarian cancer, respectively. Taxanes target microtubules in cancer cells and modifiers of taxane sensitivity have been identified in vitro, including drug efflux and mitotic checkpoint proteins. H...

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Detalles Bibliográficos
Autores principales: Corkery, Dale P, Le Page, Cécile, Meunier, Liliane, Provencher, Diane, Mes-Masson, Anne-Marie, Dellaire, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612451/
https://www.ncbi.nlm.nih.gov/pubmed/25602630
http://dx.doi.org/10.1080/15384101.2015.1007775