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The transcription factor p53: Not a repressor, solely an activator

The predominant function of the tumor suppressor p53 is transcriptional regulation. It is generally accepted that p53-dependent transcriptional activation occurs by binding to a specific recognition site in promoters of target genes. Additionally, several models for p53-dependent transcriptional rep...

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Detalles Bibliográficos
Autores principales: Fischer, Martin, Steiner, Lydia, Engeland, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612452/
https://www.ncbi.nlm.nih.gov/pubmed/25486564
http://dx.doi.org/10.4161/15384101.2014.949083