Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection

Genome editing via CRISPR/Cas9 has become an efficient and reliable way to make precise, targeted changes to the genome of living cells. CXCR4 is a co-receptor for the human immunodeficiency virus type 1 (HIV-1) infection and has been considered as an important therapeutic target for AIDS. CXCR4 med...

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Detalles Bibliográficos
Autores principales: Hou, Panpan, Chen, Shuliang, Wang, Shilei, Yu, Xiao, Chen, Yu, Jiang, Meng, Zhuang, Ke, Ho, Wenzhe, Hou, Wei, Huang, Jian, Guo, Deyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612538/
https://www.ncbi.nlm.nih.gov/pubmed/26481100
http://dx.doi.org/10.1038/srep15577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612538/
https://www.ncbi.nlm.nih.gov/pubmed/26481100
http://dx.doi.org/10.1038/srep15577

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