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Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection
Genome editing via CRISPR/Cas9 has become an efficient and reliable way to make precise, targeted changes to the genome of living cells. CXCR4 is a co-receptor for the human immunodeficiency virus type 1 (HIV-1) infection and has been considered as an important therapeutic target for AIDS. CXCR4 med...
Autores principales: | Hou, Panpan, Chen, Shuliang, Wang, Shilei, Yu, Xiao, Chen, Yu, Jiang, Meng, Zhuang, Ke, Ho, Wenzhe, Hou, Wei, Huang, Jian, Guo, Deyin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612538/ https://www.ncbi.nlm.nih.gov/pubmed/26481100 http://dx.doi.org/10.1038/srep15577 |
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