The H2 blocker famotidine suppresses progression of ossification of the posterior longitudinal ligament in a mouse model

BACKGROUND: Ossification of the posterior longitudinal ligament (OPLL) of the spine is a common human myelopathy that leads to spinal cord compression. No disease-modifying drug for OPLL has been identified, whereas surgery and conservative management have been established. OBJECTIVES: To evaluate t...

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Detalles Bibliográficos
Autores principales: Maeda, Yujiro, Yamamoto, Kenichi, Yamakawa, Akira, Aini, Hailati, Takato, Tsuyoshi, Chung, Ung-il, Ohba, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612692/
https://www.ncbi.nlm.nih.gov/pubmed/26509067
http://dx.doi.org/10.1136/rmdopen-2015-000068