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The N-cadherin cytoplasmic domain confers anchorage-independent growth and the loss of contact inhibition

Tumor growth is characterized by anchorage independence and the loss of contact inhibition. Previously, we showed that either a red fluorescent protein (DsRed)-tagged N-cadherin or E-cadherin cytoplasmic domain (DNCT or DECT) could function as a dominant negative inhibitor by blocking the cell surfa...

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Detalles Bibliográficos
Autor principal: Ozawa, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612716/
https://www.ncbi.nlm.nih.gov/pubmed/26481443
http://dx.doi.org/10.1038/srep15368