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The N-cadherin cytoplasmic domain confers anchorage-independent growth and the loss of contact inhibition
Tumor growth is characterized by anchorage independence and the loss of contact inhibition. Previously, we showed that either a red fluorescent protein (DsRed)-tagged N-cadherin or E-cadherin cytoplasmic domain (DNCT or DECT) could function as a dominant negative inhibitor by blocking the cell surfa...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612716/ https://www.ncbi.nlm.nih.gov/pubmed/26481443 http://dx.doi.org/10.1038/srep15368 |