Sirt6 depletion causes spindle defects and chromosome misalignment during meiosis of mouse oocyte

Sirt6, a member of the sirtuin family of NAD-dependent protein deacetylases, has been implicated in multiple biological processes. However, the roles of Sirt6 in meiosis have not been addressed. In the present study, by employing knockdown analysis in mouse oocytes, we evaluated the effects of Sirt6...

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Detalles Bibliográficos
Autores principales: Han, Longsen, Ge, Juan, Zhang, Liang, Ma, Rujun, Hou, Xiaojing, Li, Bin, Moley, Kelle, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612726/
https://www.ncbi.nlm.nih.gov/pubmed/26481302
http://dx.doi.org/10.1038/srep15366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612726/
https://www.ncbi.nlm.nih.gov/pubmed/26481302
http://dx.doi.org/10.1038/srep15366

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