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Divergent Inhibitor Susceptibility among Airway Lumen-Accessible Tryptic Proteases
Tryptic serine proteases of bronchial epithelium regulate ion flux, barrier integrity, and allergic inflammation. Inhibition of some of these proteases is a strategy to improve mucociliary function in cystic fibrosis and asthmatic inflammation. Several inhibitors have been tested in pre-clinical ani...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612780/ https://www.ncbi.nlm.nih.gov/pubmed/26485396 http://dx.doi.org/10.1371/journal.pone.0141169 |