Polo-like kinase 1 inhibits DNA damage response during mitosis

In response to genotoxic stress, cells protect their genome integrity by activation of a conserved DNA damage response (DDR) pathway that coordinates DNA repair and progression through the cell cycle. Extensive modification of the chromatin flanking the DNA lesion by ATM kinase and RNF8/RNF168 ubiqu...

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Detalles Bibliográficos
Autores principales: Benada, Jan, Burdová, Kamila, Lidak, Tomáš, von Morgen, Patrick, Macurek, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613155/
https://www.ncbi.nlm.nih.gov/pubmed/25607646
http://dx.doi.org/10.4161/15384101.2014.977067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613155/
https://www.ncbi.nlm.nih.gov/pubmed/25607646
http://dx.doi.org/10.4161/15384101.2014.977067

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