Monitoring of Intracellular Tau Aggregation Regulated by OGA/OGT Inhibitors

Abnormal phosphorylation of tau has been considered as a key pathogenic mechanism inducing tau aggregation in multiple neurodegenerative disorders, collectively called tauopathies. Recent evidence showed that tau phosphorylation sites are protected with O-linked β-N-acetylglucosamine (O-GlcNAc) in n...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Sungsu, Haque, Md. Mamunul, Nam, Ghilsoo, Ryoo, Nayeon, Rhim, Hyewhon, Kim, Yun Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613198/
https://www.ncbi.nlm.nih.gov/pubmed/26343633
http://dx.doi.org/10.3390/ijms160920212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613198/
https://www.ncbi.nlm.nih.gov/pubmed/26343633
http://dx.doi.org/10.3390/ijms160920212

Ejemplares similares