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BMP3 Alone and Together with TGF-β Promote the Differentiation of Human Mesenchymal Stem Cells into a Nucleus Pulposus-Like Phenotype

Human mesenchymal stem cells (MSCs) have the potential to differentiate into nucleus pulposus (NP)-like cells under specific stimulatory conditions. Thus far, the effects of bone morphogenetic protein 3 (BMP3) and the cocktail effects of BMP3 and transforming growth factor (TGF)-β on MSC proliferati...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaopeng, Tao, Yiqing, Liang, Chengzhen, Zhang, Yujie, Li, Hao, Chen, Qixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613207/
https://www.ncbi.nlm.nih.gov/pubmed/26343641
http://dx.doi.org/10.3390/ijms160920344