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A Series of New Ligustrazine-Triterpenes Derivatives as Anti-Tumor Agents: Design, Synthesis, and Biological Evaluation

A series of novel ligustrazine-triterpenes derivatives was designed, synthesized and screened for their cytotoxicity against five cancer cell lines (Bel-7402, HepG2, HT-29, Hela, and MCF-7) and Madin-Darby canine kidney (MDCK). Current study suggested that most of the ligustrazine-triterpenes conjun...

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Detalles Bibliográficos
Autores principales: Xu, Bing, Chu, Fuhao, Zhang, Yuzhong, Wang, Xiaobo, Li, Qiang, Liu, Wei, Xu, Xin, Xing, Yanyi, Chen, Jing, Wang, Penglong, Lei, Haimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613240/
https://www.ncbi.nlm.nih.gov/pubmed/26404253
http://dx.doi.org/10.3390/ijms160921035