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Weekly Treatment of 2-Hydroxypropyl-β-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice

Recently, the importance of lysosomes in the context of the metabolic syndrome has received increased attention. Increased lysosomal cholesterol storage and cholesterol crystallization inside macrophages have been linked to several metabolic diseases, such as atherosclerosis and non-alcoholic fatty...

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Detalles Bibliográficos
Autores principales: Walenbergh, Sofie M. A., Houben, Tom, Hendrikx, Tim, Jeurissen, Mike L. J., van Gorp, Patrick J., Vaes, Nathalie, Olde Damink, Steven W. M., Verheyen, Fons, Koek, Ger H., Lütjohann, Dieter, Grebe, Alena, Latz, Eicke, Shiri-Sverdlov, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613241/
https://www.ncbi.nlm.nih.gov/pubmed/26404254
http://dx.doi.org/10.3390/ijms160921056