Exploring the Molecular Interactions of 7,8-Dihydroxyflavone and Its Derivatives with TrkB and VEGFR2 Proteins

7,8-Dihydroxyflavone (7,8-DHF) is a TrkB receptor agonist, and treatment with this flavonoid derivative brings about an enhanced TrkB phosphorylation and promotes downstream cellular signalling. Flavonoids are also known to exert an inhibitory effect on the vascular endothelial growth factor recepto...

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Detalles Bibliográficos
Autores principales: Chitranshi, Nitin, Gupta, Vivek, Kumar, Sanjay, Graham, Stuart L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613243/
https://www.ncbi.nlm.nih.gov/pubmed/26404256
http://dx.doi.org/10.3390/ijms160921087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613243/
https://www.ncbi.nlm.nih.gov/pubmed/26404256
http://dx.doi.org/10.3390/ijms160921087

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