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Single-Base Pair Genome Editing in Human Cells by Using Site-Specific Endonucleases
Genome-wide association studies have identified numerous single-nucleotide polymorphisms (SNPs) associated with human diseases or phenotypes. However, causal relationships between most SNPs and the associated disease have not been established, owing to technical challenges such as unavailability of...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613245/ https://www.ncbi.nlm.nih.gov/pubmed/26404258 http://dx.doi.org/10.3390/ijms160921128 |