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PI3K and AKT: Unfaithful Partners in Cancer

The phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway regulates multiple cellular processes. An overactivation of the pathway is frequently present in human malignancies and plays a key role in cancer progression. Hence, its inhibition has become a promising approach in cancer therapy. Howe...

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Detalles Bibliográficos
Autores principales: Faes, Seraina, Dormond, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613246/
https://www.ncbi.nlm.nih.gov/pubmed/26404259
http://dx.doi.org/10.3390/ijms160921138