SOX2 Promotes the Epithelial to Mesenchymal Transition of Esophageal Squamous Cells by Modulating Slug Expression through the Activation of STAT3/HIF-α Signaling

The transcription factor sex determining region (Y SRY)-box 2 (SOX2) is known to play a crucial role in the maintenance of self renewal or pluripotency of undifferentiated embryonic and neuronal stem cells. An elevated expression of SOX2 has been correlated with poor prognosis of esophageal squamous...

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Detalles Bibliográficos
Autores principales: Gao, Hui, Teng, Chunyuan, Huang, Wenjing, Peng, Jianjun, Wang, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613272/
https://www.ncbi.nlm.nih.gov/pubmed/26370982
http://dx.doi.org/10.3390/ijms160921643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613272/
https://www.ncbi.nlm.nih.gov/pubmed/26370982
http://dx.doi.org/10.3390/ijms160921643

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