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Adaptive Immune Responses in a Multiple Sclerosis Patient with Acute Varicella-Zoster Virus Reactivation during Treatment with Fingolimod

Fingolimod, an oral sphingosine 1-phosphate (S1P) receptor modulator, is approved for the treatment of relapsing forms of multiple sclerosis (MS). The interference with S1P signaling leads to retention particularly of chemokine receptor-7 (CCR7) expressing T cells in lymph nodes. The immunological b...

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Detalles Bibliográficos
Autores principales: Harrer, Andrea, Wipfler, Peter, Pilz, Georg, Oppermann, Katrin, Haschke-Becher, Elisabeth, Afazel, Shahrzad, Kraus, Jörg, Trinka, Eugen, Sellner, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613283/
https://www.ncbi.nlm.nih.gov/pubmed/26378517
http://dx.doi.org/10.3390/ijms160921832