Gardenamide A Protects RGC-5 Cells from H(2)O(2)-Induced Oxidative Stress Insults by Activating PI3K/Akt/eNOS Signaling Pathway

Gardenamide A (GA) protects the rat retinal ganglion (RGC-5) cells against cell apoptosis induced by H(2)O(2). The protective effect of GA was completely abrogated by the specific phosphoinositide 3-kinase (PI3K) inhibitor LY294002, and the specific protein kinase B (Akt) inhibitor Akt VIII respecti...

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Detalles Bibliográficos
Autores principales: Wang, Rikang, Peng, Lizhi, Zhao, Jiaqiang, Zhang, Laitao, Guo, Cuiping, Zheng, Wenhua, Chen, Heru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613312/
https://www.ncbi.nlm.nih.gov/pubmed/26389892
http://dx.doi.org/10.3390/ijms160922350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613312/
https://www.ncbi.nlm.nih.gov/pubmed/26389892
http://dx.doi.org/10.3390/ijms160922350

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