Expression of PD-1 Molecule on Regulatory T Lymphocytes in Patients with Insulin-Dependent Diabetes Mellitus

Type 1 diabetes is caused by autoreactive T cells that destroy pancreatic beta cells. Animal models suggested that a CD4(+)CD25(+) population has a regulatory function capable of preventing activation and effector functions of autoreactive T cells. However, the role of CD4(+)CD25(high) T cells in au...

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Detalles Bibliográficos
Autores principales: Perri, Valentina, Russo, Benedetta, Crinò, Antonino, Schiaffini, Riccardo, Giorda, Ezio, Cappa, Marco, Rosado, Maria Manuela, Fierabracci, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613325/
https://www.ncbi.nlm.nih.gov/pubmed/26393578
http://dx.doi.org/10.3390/ijms160922584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613325/
https://www.ncbi.nlm.nih.gov/pubmed/26393578
http://dx.doi.org/10.3390/ijms160922584

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