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Rational Protein Engineering Guided by Deep Mutational Scanning
Sequence–function relationship in a protein is commonly determined by the three-dimensional protein structure followed by various biochemical experiments. However, with the explosive increase in the number of genome sequences, facilitated by recent advances in sequencing technology, the gap between...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613353/ https://www.ncbi.nlm.nih.gov/pubmed/26404267 http://dx.doi.org/10.3390/ijms160923094 |