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Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury

COPD (chronic obstructive pulmonary disease) is associated with sustained inflammation, excessive injury, and accelerated lung aging. Human Klotho (KL) is an anti-aging protein that protects cells against inflammation and damage. In the present study, we quantified KL expression in the lungs of COPD...

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Detalles Bibliográficos
Autores principales: Gao, Wei, Yuan, Cheng, Zhang, Jingying, Li, Lingling, Yu, Like, Wiegman, Coen H., Barnes, Peter J., Adcock, Ian M., Huang, Mao, Yao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613497/
https://www.ncbi.nlm.nih.gov/pubmed/26201096
http://dx.doi.org/10.1042/CS20150273