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The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2–ezrin binding and dexamethasone stimulated NHE3 activity

In the brush border of intestinal and kidney epithelial cells, scaffolding proteins ezrin, Na(+)-H(+) exchanger regulatory factor (NHERF)1 and NHERF2 play important roles in linking transmembrane proteins to the cytoskeleton and assembling signalling regulatory complexes. The last 30 carboxyl residu...

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Detalles Bibliográficos
Autores principales: Yang, Jianbo, Sarker, Rafiquel, Singh, Varsha, Sarker, Prateeti, Yin, Jianyi, Chen, Tian-E, Chaerkady, Raghothama, Li, Xuhang, Tse, C. Ming, Donowitz, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613507/
https://www.ncbi.nlm.nih.gov/pubmed/26251448
http://dx.doi.org/10.1042/BJ20150238