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The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2–ezrin binding and dexamethasone stimulated NHE3 activity
In the brush border of intestinal and kidney epithelial cells, scaffolding proteins ezrin, Na(+)-H(+) exchanger regulatory factor (NHERF)1 and NHERF2 play important roles in linking transmembrane proteins to the cytoskeleton and assembling signalling regulatory complexes. The last 30 carboxyl residu...
Autores principales: | Yang, Jianbo, Sarker, Rafiquel, Singh, Varsha, Sarker, Prateeti, Yin, Jianyi, Chen, Tian-E, Chaerkady, Raghothama, Li, Xuhang, Tse, C. Ming, Donowitz, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613507/ https://www.ncbi.nlm.nih.gov/pubmed/26251448 http://dx.doi.org/10.1042/BJ20150238 |
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