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Interplay between cytosolic disulfide reductase systems and the Nrf2/Keap1 pathway
NADPH transfers reducing power from bioenergetic pathways to thioredoxin reductase-1 (TrxR1) and glutathione reductase (GR) to support essential reductive systems. Surprisingly, it was recently shown that mouse livers lacking both TrxR1 and GR (‘TR/GR-null’) can sustain redox (reduction-oxidation) h...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Portland Press Ltd.
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613508/ https://www.ncbi.nlm.nih.gov/pubmed/26551704 http://dx.doi.org/10.1042/BST20150021 |