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The spatiotemporal regulation of the Keap1–Nrf2 pathway and its importance in cellular bioenergetics
The Kelch-like ECH associated protein 1 (Keap1)–NF-E2 p45-related factor 2 (Nrf2) pathway regulates networks of proteins that protect against the cumulative damage of oxidants, electrophiles and misfolded proteins. The interaction between transcription factor Nrf2 and its main negative cytoplasmic r...
Autores principales: | Dinkova-Kostova, Albena T., Baird, Liam, Holmström, Kira M., Meyer, Colin J., Abramov, Andrey Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613514/ https://www.ncbi.nlm.nih.gov/pubmed/26551700 http://dx.doi.org/10.1042/BST20150003 |
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