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The spatiotemporal regulation of the Keap1–Nrf2 pathway and its importance in cellular bioenergetics

The Kelch-like ECH associated protein 1 (Keap1)–NF-E2 p45-related factor 2 (Nrf2) pathway regulates networks of proteins that protect against the cumulative damage of oxidants, electrophiles and misfolded proteins. The interaction between transcription factor Nrf2 and its main negative cytoplasmic r...

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Detalles Bibliográficos
Autores principales: Dinkova-Kostova, Albena T., Baird, Liam, Holmström, Kira M., Meyer, Colin J., Abramov, Andrey Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613514/
https://www.ncbi.nlm.nih.gov/pubmed/26551700
http://dx.doi.org/10.1042/BST20150003