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Value of monitoring Nrf2 activity for the detection of chemical and oxidative stress

Beyond specific limits of exposure, chemical entities can provoke deleterious effects in mammalian cells via direct interaction with critical macromolecules or by stimulating the accumulation of reactive oxygen species (ROS). In particular, these chemical and oxidative stresses can underpin adverse...

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Detalles Bibliográficos
Autores principales: Mutter, Fiona E., Park, B. Kevin, Copple, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613517/
https://www.ncbi.nlm.nih.gov/pubmed/26551708
http://dx.doi.org/10.1042/BST20150044