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Value of monitoring Nrf2 activity for the detection of chemical and oxidative stress
Beyond specific limits of exposure, chemical entities can provoke deleterious effects in mammalian cells via direct interaction with critical macromolecules or by stimulating the accumulation of reactive oxygen species (ROS). In particular, these chemical and oxidative stresses can underpin adverse...
Autores principales: | Mutter, Fiona E., Park, B. Kevin, Copple, Ian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613517/ https://www.ncbi.nlm.nih.gov/pubmed/26551708 http://dx.doi.org/10.1042/BST20150044 |
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