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Transition metals activate TFEB in overexpressing cells

Transition metal toxicity is an important factor in the pathogenesis of numerous human disorders, including neurodegenerative diseases. Lysosomes have emerged as important factors in transition metal toxicity because they handle transition metals via endocytosis, autophagy, absorption from the cytop...

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Detalles Bibliográficos
Autores principales: Peña, Karina A., Kiselyov, Kirill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613523/
https://www.ncbi.nlm.nih.gov/pubmed/26251447
http://dx.doi.org/10.1042/BJ20140645