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Nuclear transcriptome profiling of induced pluripotent stem cells and embryonic stem cells identify non-coding loci resistant to reprogramming

Identification of functionally relevant differences between induced pluripotent stem cells (iPSC) and reference embryonic stem cells (ESC) remains a central question for therapeutic applications. Differences in gene expression between iPSC and ESC have been examined by microarray and more recently w...

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Detalles Bibliográficos
Autores principales: Fort, Alexandre, Yamada, Daisuke, Hashimoto, Kosuke, Koseki, Haruhiko, Carninci, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613594/
https://www.ncbi.nlm.nih.gov/pubmed/25664506
http://dx.doi.org/10.4161/15384101.2014.988031