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A Double-Blind, Placebo-Controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of JDTic

Animal studies suggest that kappa opioid receptor antagonists (KORAn) potentially could treat a wide variety of addictive and depressive disorders. We assessed the KORAn JDTic for safety, tolerability, and pharmacokinetics in a double-blind, placebo-controlled, randomized trial evaluating single ora...

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Detalles Bibliográficos
Autores principales: Buda, Jeffrey J, Carroll, F I, Kosten, Thomas R, Swearingen, Dennis, Walters, Bradford B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613600/
https://www.ncbi.nlm.nih.gov/pubmed/25628006
http://dx.doi.org/10.1038/npp.2015.27