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Reducing Ventral Tegmental Dopamine D2 Receptor Expression Selectively Boosts Incentive Motivation

Altered mesolimbic dopamine signaling has been widely implicated in addictive behavior. For the most part, this work has focused on dopamine within the striatum, but there is emerging evidence for a role of the auto-inhibitory, somatodendritic dopamine D2 receptor (D2R) in the ventral tegmental area...

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Detalles Bibliográficos
Autores principales: de Jong, Johannes W, Roelofs, Theresia J M, Mol, Frédérique M U, Hillen, Anne E J, Meijboom, Katharina E, Luijendijk, Mieneke C M, van der Eerden, Harrie A M, Garner, Keith M, Vanderschuren, Louk J M J, Adan, Roger A H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613606/
https://www.ncbi.nlm.nih.gov/pubmed/25735756
http://dx.doi.org/10.1038/npp.2015.60