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Reducing Ventral Tegmental Dopamine D2 Receptor Expression Selectively Boosts Incentive Motivation
Altered mesolimbic dopamine signaling has been widely implicated in addictive behavior. For the most part, this work has focused on dopamine within the striatum, but there is emerging evidence for a role of the auto-inhibitory, somatodendritic dopamine D2 receptor (D2R) in the ventral tegmental area...
Autores principales: | de Jong, Johannes W, Roelofs, Theresia J M, Mol, Frédérique M U, Hillen, Anne E J, Meijboom, Katharina E, Luijendijk, Mieneke C M, van der Eerden, Harrie A M, Garner, Keith M, Vanderschuren, Louk J M J, Adan, Roger A H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613606/ https://www.ncbi.nlm.nih.gov/pubmed/25735756 http://dx.doi.org/10.1038/npp.2015.60 |
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