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3D spheroid cultures improve the metabolic gene expression profiles of HepaRG cells

3D (three-dimensional) cultures are considered to be an effective method for toxicological studies; however, little evidence has been reported whether 3D cultures have an impact on hepatocellular physiology regarding lipid or glucose metabolism. In the present study, we conducted physiological chara...

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Detalles Bibliográficos
Autores principales: Takahashi, Yu, Hori, Yuji, Yamamoto, Tomohisa, Urashima, Toshiki, Ohara, Yasunori, Tanaka, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613666/
https://www.ncbi.nlm.nih.gov/pubmed/26182370
http://dx.doi.org/10.1042/BSR20150034