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Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death

Protein targeting to glycogen (PTG) is a ubiquitously expressed scaffolding protein that critically regulates glycogen levels in many tissues, including the liver, muscle and brain. However, its importance in transformed cells has yet to be explored in detail. Since recent studies have demonstrated...

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Detalles Bibliográficos
Autores principales: Yang, Rongqiang, Zhang, Mei, Gustafson, Amber Renee, Wang, Eugenia, Cole, Marsha Paulette, Tooley, Christine Elizabeth Schaner, Cheng, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613675/
https://www.ncbi.nlm.nih.gov/pubmed/26182369
http://dx.doi.org/10.1042/BSR20150090