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∆Np73 is capable of inducing apoptosis by co-ordinately activating several BH3-only proteins
Inactivation of p53 is one of the most relevant events in human cancer, since it allows transformed cells to escape their own proliferation control and leave them irresponsive to drugs that aim to damage their DNA. When p53 falls, other members of its family may become targets to attack tumoural cel...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613676/ https://www.ncbi.nlm.nih.gov/pubmed/26182360 http://dx.doi.org/10.1042/BSR20150039 |