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Molecular determinants of ATP-sensitive potassium channel MgATPase activity: diabetes risk variants and diazoxide sensitivity

ATP-sensitive K(+) (K(ATP)) channels play an important role in insulin secretion. K(ATP) channels possess intrinsic MgATPase activity that is important in regulating channel activity in response to metabolic changes, although the precise structural determinants are not clearly understood. Furthermor...

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Detalles Bibliográficos
Autores principales: Fatehi, Mohammad, Carter, Chris R.J., Youssef, Nermeen, Hunter, Beth E., Holt, Andrew, Light, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613687/
https://www.ncbi.nlm.nih.gov/pubmed/26181369
http://dx.doi.org/10.1042/BSR20150143