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Molecular determinants of ATP-sensitive potassium channel MgATPase activity: diabetes risk variants and diazoxide sensitivity
ATP-sensitive K(+) (K(ATP)) channels play an important role in insulin secretion. K(ATP) channels possess intrinsic MgATPase activity that is important in regulating channel activity in response to metabolic changes, although the precise structural determinants are not clearly understood. Furthermor...
Autores principales: | Fatehi, Mohammad, Carter, Chris R.J., Youssef, Nermeen, Hunter, Beth E., Holt, Andrew, Light, Peter E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613687/ https://www.ncbi.nlm.nih.gov/pubmed/26181369 http://dx.doi.org/10.1042/BSR20150143 |
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