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Stress-mediated Sin3B activation leads to negative regulation of subset of p53 target genes

The multiprotein SWI-independent 3 (Sin3)–HDAC (histone deacetylase) corepressor complex mediates gene repression through its interaction with DNA-binding factors and recruitment of chromatin-modifying proteins on to the promoters of target gene. Previously, an increased expression of Sin3B and tumo...

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Detalles Bibliográficos
Autores principales: Kadamb, Rama, Mittal, Shilpi, Bansal, Nidhi, Saluja, Daman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613689/
https://www.ncbi.nlm.nih.gov/pubmed/26181367
http://dx.doi.org/10.1042/BSR20150122