Insulin down-regulates the expression of ubiquitin E3 ligases partially by inhibiting the activity and expression of AMP-activated protein kinase in L6 myotubes

While insulin is an anabolic hormone, AMP-activated protein kinase (AMPK) is not only a key energy regulator, but it can also control substrate metabolism directly by inducing skeletal muscle protein degradation. The hypothesis of the present study was that insulin inhibits AMPK and thus down-regula...

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Detalles Bibliográficos
Autores principales: Deng, Hu-Ping, Chai, Jia-Ke, Shen, Chuan-An, Zhang, Xi-Bo, Ma, Li, Sun, Tian-Jun, Hu, Qing-Gang, Chi, Yun-Fei, Dong, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613693/
https://www.ncbi.nlm.nih.gov/pubmed/26193886
http://dx.doi.org/10.1042/BSR20150017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613693/
https://www.ncbi.nlm.nih.gov/pubmed/26193886
http://dx.doi.org/10.1042/BSR20150017

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