PGC-1α limits angiotensin II-induced rat vascular smooth muscle cells proliferation via attenuating NOX1-mediated generation of reactive oxygen species

AngII (angiotensin II)-induced excessive ROS (reactive oxygen species) generation and proliferation of VSMCs (vascular smooth muscle cells) is a critical contributor to the pathogenesis of atherosclerosis. PGC-1α [PPARγ (peroxisome-proliferator-activated receptor γ) co-activator-1α] is involved in t...

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Detalles Bibliográficos
Autores principales: Zhao, Qingbin, Zhang, Junfang, Wang, Huifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613698/
https://www.ncbi.nlm.nih.gov/pubmed/26310573
http://dx.doi.org/10.1042/BSR20150112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613698/
https://www.ncbi.nlm.nih.gov/pubmed/26310573
http://dx.doi.org/10.1042/BSR20150112

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