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Uncoupling protein 2 mediates resistance to gemcitabine-induced apoptosis in hepatocellular carcinoma cell lines

Oxidative stress induction is a common effector pathway for commonly used chemotherapeutic agents like gemcitabine (GEM) in hepatocellular carcinoma (HCC) patients. However, GEM alone or in combination with oxiplatin hardly renders any survival benefits to HCC patients. Mitochondrial uncoupling prot...

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Detalles Bibliográficos
Autores principales: Yu, Guangsheng, Liu, Jun, Xu, Kesen, Dong, Jiahong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613703/
https://www.ncbi.nlm.nih.gov/pubmed/26181366
http://dx.doi.org/10.1042/BSR20150116