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Cardioprotective effects and pharmacokinetic properties of a controlled release formulation of a novel hydrogen sulfide donor in rats with acute myocardial infarction

We previously reported that S-propargyl-cysteine (SPRC) exerts cardioprotective effects by elevating H(2)S levels via the CSE/H(2)S pathway. In the present study, we investigated the cardioprotective effects and pharmacokinetic properties of a controlled release formulation of SPRC (CR-SPRC) in an i...

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Detalles Bibliográficos
Autores principales: Tran, Ba Hieu, Huang, Chengrong, Zhang, Qiuyan, Liu, Xu, Lin, Shizhou, Liu, Hongrui, Wang, Shujun, Zhu, Yi Zhun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613708/
https://www.ncbi.nlm.nih.gov/pubmed/26182378
http://dx.doi.org/10.1042/BSR20140185