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Cysteine-specific ubiquitination protects the peroxisomal import receptor Pex5p against proteasomal degradation

Peroxisomal matrix protein import is mediated by dynamic import receptors, which cycle between the peroxisomal membrane and the cytosol. Proteins with a type 1 peroxisomal targeting signal (PTS1) are bound by the import receptor Pex5p in the cytosol and guided to the peroxisomal membrane. After carg...

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Detalles Bibliográficos
Autores principales: Schwartzkopff, Benjamin, Platta, Harald W., Hasan, Sohel, Girzalsky, Wolfgang, Erdmann, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613714/
https://www.ncbi.nlm.nih.gov/pubmed/26182377
http://dx.doi.org/10.1042/BSR20150103