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NRG1 and KITL signal downstream of retinoic acid in the germline to support soma-free syncytial growth of differentiating spermatogonia

Defined culture systems supporting spermatogonial differentiation will provide experimental platforms to study spermatogenesis. However, germline-intrinsic signaling mechanisms sufficient to support spermatogonial differentiation without somatic cells remain largely undefined. Here we analyzed EGF s...

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Detalles Bibliográficos
Autores principales: Chapman, KM, Medrano, GA, Chaudhary, J, Hamra, FK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613782/
https://www.ncbi.nlm.nih.gov/pubmed/26500786
http://dx.doi.org/10.1038/cddiscovery.2015.18